Objective: To summarize the data on the clinical features, treatments, and prognosis in 21 patients with diabetic ketoacidosis (DKA) complicated by multiple organ dysfunction syndrome (MODS). Methods: The clinical data on 21 patients with DKA complicated by MODS treated in Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus from February 2015 to February 2017 were collected, and the pathogenesis, manifestations, treatment principles and method, and prognosis and so forth of DKA complicated by MODS were investigated. Results: Infection was the main inducement in these 21 patients with DKA complicated by MODS. Based on the routine medical treatments, quickly dripping insulin could effectively relieve the clinical manifestations of ketoacidosis and improve the prognosis of DKA complicated by MODS. The cure rate and death rate of the combined modality therapy were 85.71% and 14.29%, respectively. There was no significant difference between the cure rate and mortality of DKA with MODS (P>0.05). Conclusion: DKA complicated by MODS has complicated causative factors, critical conditions, and ominous prognosis. Combined modality therapy (quickly dripping insulin combined with routine medical treatments) should be given in time according to different conditions, and directed treatments be given based on the clinical features and causative factors.
[1]Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Crit Care Med, South Campus,6600 Nanfeng Rd, Shanghai 201499, Peoples R China.
(8.0+极速模式)