We evaluate the differences between primary diffuse large B-cell lymphoma (DLBCL) and mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach on multi-detector computed tomography (MDCT) to better define the radiological hallmarks of primary gastric lymphoma. We retrospectively reviewed the contrast enhanced MDCT scans of 33 patients with pathological diagnoses of DLBCL (n=23) and MALT lymphoma (n=10), as well as 1 case of DLBCL associated with MALT lymphoma. The MDCT findings of each case were analyzed for tumor location, tumor type, gastric wall thickness, enhancement and infiltration of gastric serosa, and the presence of perigastric lymph nodes. The 23 DLBCL patients were subdivided based on the type of lesion observed on MDCT and included tumoral (n=5, 21.7%), nodular (n=1, 4.3%), ulcerative (n=5, 21.7%), and infiltrative types (n=12, 52.2%). The 10 cases of MALT lymphoma were all classified as infiltrative on MDCT. The mean gastric wall thickness was 19.43 mm (range: 6-68 mm) in the DLBCL group compared to 10.75 mm (range: 6-22 mm) in the MALT lymphoma group. No statistically significant difference in gastric wall enhancement was noted between groups, though serosal infiltration was significantly greater in the DLBCL group (52.2% infiltrative) compared to the MALT lymphoma group (30.0% infiltrative). Relatively increased gastric wall thickness, gastric stenosis, epigastric serosal infiltration, and perigastric lymphadenopathy may be suggestive of DLBCL on MDCT. While classification of primary gastric lymphoma using MDCT may be possible, larger scale studies are necessary to determine the true radiological diagnostic potential.
[1]Yanbian Univ, Affiliated Hosp, Dept Radiol, Yanji 133000, Peoples R China.
[2]Zibo Cent Hosp, Dept Radiol, Zibo 255020, Peoples R China.
[3]Shanghai Jiao Tong Univ, Dept Radiol, Peoples Hosp 6, 222 Huanhu West 3 Rd, Shanghai 201306, Peoples R China.
(8.0+极速模式)