Objective: This study aims to examine the plaque properties of stable coronary heart disease patients with coronary intermediate lesion by virtual histology-intravascular ultrasound imaging (VH-IVUS). Methods: From Feb. 2015 to Dec. 2016, patients in our hospital with stable coronary heart disease were identified as coronary intermediate lesion by receiving coronary angiography examination. The screening patients were further received VH-IVUS to evaluate the plaque character. Results: A total of 265 coronary intermediate lesion patients were included in the study. The average age is 66.93 +/- 9.75. Among the cases, thin-cap fibroatheroma (TCFA) is 127; thick-cap fibroatheroma (ThCFA) is 93; pathological intimal thickening (PIT) is 41; fibrotic plaque (FT) is 4; fibrocalcific plaque (FC) is 0. Compared with ThCFA, TCFA had more cases of diabetes and hyperlipidemia. Compared with ThCFA and PIT, TCFA patients had coronary artery atheromatous plaque more than 10% of necrotic core of plaque area, increased high density calcified components, more cases with the minimal lumen area < 4.0 mm(2). Conclusion: The dominated plague type of coronary intermediate lesion is TCFA/ThCFA. TCFA combined with plague load and clinical symptom might be regarded as the basis for the evaluating the unstable condition of stable coronary heart disease patients.
[1]Shanghai Univ Med & Hlth Sci, Shanghai Pudong New Area Zhoupu Hosp, Dept Cardiol, Shanghai 201318, Peoples R China.
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