首页 / 院系成果 / 成果详情页

m2: a Multi-Center Study with a 4-Year Follow-Up of Surgical Cohort 期刊论文

编号：

8f8430fa-93ed-4fda-a42c-3ba2c201e690
作者：

Tu, Yinfang#^[1]Wang, Liang#^[2,3,4]Wei, Li(魏丽)^[5]Xu, Youhao^[6];Han, Xiaodong^[7];Han, Junfeng^[1];Yu, Haoyong^[1];Zheng, Chao^[2,3,4];Bao, Yuqian*^[1]Jia, Weiping*^[1]
语种：

英文
期刊：

OBESITY SURGERY ISSN：0960-8923 2019 年 29 卷 12 期 (3978 - 3986) ; DEC
收录：
关键词：

Cost-utility analysis(CUA) Quality-adjusted life years (QALY) roux-en-Y gastric bypass (RYGB) Body mass index (BMI) Glycated hemoglobin A1c (A1C) Total healthcare costs Type 2 diabetes (T2D) Obesity
摘要：

Objectives To find whether Laparoscopic Roux-en-Y gastric bypass (RYGB) surgery was cost effective compared to conventional medical management (CMM) in Chinese patients with type 2 Diabetes(T2D) and obesity with a body mass index (BMI) >= 27.5 kg/m(2) in four years.
Methods A total of 106 obese T2D individuals who underwent RYGB and 106 T2D patients treated with CMM were enrolled from three academic medical centers. Total health related costs, Glycated Hemoglobin A1c (A1C) and BMI was recorded. Cost-Utility Analysis (CUA) was used. Utility values according to results of A1c were obtained from published studies.
Results Improvements were observed in A1C (8.6% at baseline to 6.2% in the first year, p < 0.001) and BMI (30.7 kg/m(2) at baseline to 24.3 kg/m(2) in the first year, p < 0.001), and the effect lasted for 4 years after RYGB. In the CMM group, A1C fluctuated in four years. The health utility for RYGB group scores 3.756, whereas CMM group scores 3.594 in four years. The total healthcare costs decreased sharply from the second year after RYGB ($8,483 [(sic)52,596] in the first year to $672[(sic)4,164] in the second year, p < 0.001) and maintained for 3 years. In the CMM group, the total healthcare costs changed without significance. RYGB costs US$19,359 ((sic)125,836) per quality-adjusted life years (QALY) gained (incremental cost-utility ratio [ICUR]) compared to CMM, which was lower than a willingness-to-pay (WTP) of $20,277/QALY.
Conclusions Compared to CMM, RYGB is cost-effective for Chinese patients with type 2 diabetes and obesity 4 years after operation.
推荐引用方式
GB/T 7714：

Tu Yinfang,Wang Liang,Wei Li, et al. Cost-Utility of Laparoscopic Roux-en-Y Gastric Bypass in Chinese Patients with Type 2 Diabetes and Obesity with a BMI >= 27.5 kg/m2: a Multi-Center Study with a 4-Year Follow-Up of Surgical Cohort [J].OBESITY SURGERY,2019,29(12):3978-3986.
APA：

Tu Yinfang,Wang Liang,Wei Li,Xu Youhao,&Jia Weiping.(2019).Cost-Utility of Laparoscopic Roux-en-Y Gastric Bypass in Chinese Patients with Type 2 Diabetes and Obesity with a BMI >= 27.5 kg/m2: a Multi-Center Study with a 4-Year Follow-Up of Surgical Cohort .OBESITY SURGERY,29(12):3978-3986.
MLA：

Tu Yinfang, et al. "Cost-Utility of Laparoscopic Roux-en-Y Gastric Bypass in Chinese Patients with Type 2 Diabetes and Obesity with a BMI >= 27.5 kg/m2: a Multi-Center Study with a 4-Year Follow-Up of Surgical Cohort" .OBESITY SURGERY 29,12(2019):3978-3986.
入库时间：

9/25/2019 10:42:54 AM
更新时间：

9/25/2019 10:42:54 AM
条目包含文件：

文件类型：PDF,文件大小：

正在加载全文

未找到全文

浏览次数：78  下载次数：0

分享到：

浏览次数：78

下载次数：0

打印次数：0